Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.44 |
| ▸ | SNCA | P37840 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | TYR | P14679 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 2/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3862519 | 1.00 | APP (0.52) | APPALDH1A1GAAERAP1SNCA | |
| SCHEMBL532189 | 0.87 | APP (0.55) | APPALDH1A1GAAERAP1SNCA | |
| SCHEMBL3862517 | 0.85 | MAPT (0.55) | ALDH1A1GAAMAPTMEN1KMT2A | |
| SCHEMBL24767122 | 0.83 | APP (0.53) | APPALDH1A1GAASNCAMAPT | |
| SCHEMBL327849 | 0.76 | APP (0.63) | APPALDH1A1GAASNCAMAPT | |
| SCHEMBL9538491 | 0.75 | PTPN1 (0.50) | ALDH1A1MAPTMEN1KMT2ATDP1 | |
| SCHEMBL9539379 | 0.75 | PTPN1 (0.50) | ALDH1A1MAPTMEN1KMT2ATDP1 | |
| SCHEMBL6595318 | 0.75 | MAPT (0.50) | APPALDH1A1GAAERAP1ALOX15 | |
| Decanoic Acid SCHEMBL6708176 | 0.75 | APP (0.68) | APPALDH1A1GAAHTTTSHR | |
| Octanoic Acid SCHEMBL21043903 | 0.75 | APP (0.68) | APPALDH1A1GAAHTTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5242805-A | Useful in directingcells producing enzymes that hydrolyze the glycoside | MOLECULAR PROBES, INC. (US) | 1993-09-07 | — | — | US | disclosed |
| WO-1993004074-A1 | LONG WAVELENGTH LIPOPHILIC FLUOROGENIC GLYCOSIDASE SUBSTRATES | MOLECULAR PROBES, INC. (US) | 1993-03-04 | — | — | WO | disclosed |