Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 12/20 | 0.72 |
| ▸ | ITGB2 | P05107 | 2/20 | 0.52 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.52 |
| ▸ | ITGAL | P20701 | 2/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5732433 | 0.84 | SLC6A4 (1.00) | SLC6A4SLC6A2SLC6A3 | |
| Hydrochloric Acid SCHEMBL9464818 | 0.83 | SLC6A4 (0.97) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL9541406 | 0.82 | SLC6A4 (0.92) | SLC6A4ITGB2ICAM1ITGALSLC6A2 | |
| SCHEMBL4437763 | 0.82 | SLC6A4 (0.75) | SLC6A4ITGB2ICAM1ITGALSLC6A2 | |
| Hydrochloric Acid SCHEMBL9541705 | 0.81 | SLC6A4 (0.89) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL9541726 | 0.80 | SLC6A4 (0.76) | SLC6A4SLC6A2SLC6A3 | |
| Hydrochloric Acid SCHEMBL9541354 | 0.79 | SLC6A4 (0.74) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL9541450 | 0.77 | SLC6A4 (0.82) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL11760094 | 0.77 | SLC6A4 (0.57) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL4440726 | 0.77 | SLC6A4 (0.66) | SLC6A4ITGB2ICAM1ITGALSLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993012080-A1 | SUBSTITUTED DIPHENYLSULFIDES AS SEROTONIN UPTAKE INHIBITORS | THE WELLCOME FOUNDATION LIMITED (GB) | 1993-06-24 | — | — | WO | disclosed |