Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK13 | O15264 | 10/20 | 0.53 |
| ▸ | MAPK12 | P53778 | 10/20 | 0.53 |
| ▸ | MAPK11 | Q15759 | 10/20 | 0.53 |
| ▸ | MAPK14 | Q16539 | 10/20 | 0.53 |
| ▸ | RAF1 | P04049 | 6/20 | 0.53 |
| ▸ | MAPK9 | P45984 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | GCGR | P47871 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzene SCHEMBL28852698 | 0.77 | MAPK13 (0.82) | MAPK13MAPK12MAPK11MAPK14RAF1 | |
| SCHEMBL104130 | 0.77 | MAPK13 (0.82) | MAPK13MAPK12MAPK11MAPK14RAF1 | |
| SCHEMBL724250 | 0.75 | NPY5R (0.72) | MAPK13MAPK12MAPK11MAPK14RAF1 | |
| SCHEMBL5074753 | 0.75 | MAPK13 (0.83) | MAPK13MAPK12MAPK11MAPK14RAF1 | |
| SCHEMBL27850480 | 0.75 | MAPK13 (0.79) | MAPK13MAPK12MAPK11MAPK14RAF1 | |
| Methane SCHEMBL3278320 | 0.75 | MAPK13 (0.79) | MAPK13MAPK12MAPK11MAPK14RAF1 | |
| SCHEMBL27914820 | 0.75 | MAPK13 (0.53) | MAPK13MAPK12MAPK11MAPK14RAF1 | |
| SCHEMBL5361379 | 0.75 | POLB (0.53) | MAPK13MAPK12MAPK11MAPK14RAF1 | |
| SCHEMBL16667652 | 0.73 | MAPK13 (0.83) | MAPK13MAPK12MAPK11MAPK14RAF1 | |
| SCHEMBL31305589 | 0.72 | NPY5R (0.68) | MAPK13MAPK12MAPK11MAPK14RAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993001183-A1 | IMIDAZOLE DERIVATIVE AS ACAT INHIBITOR | RHONE-POULENC RORER LIMITED (GB) | 1993-01-21 | — | — | WO | disclosed |