Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 3/20 | 0.77 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.77 |
| ▸ | GAA | P10253 | 4/20 | 0.58 |
| ▸ | HTR6 | P50406 | 2/20 | 0.56 |
| ▸ | PKM | P14618 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10869434 | 0.83 | GRIN1 (0.74) | GRIN2BGRIN1GAAPDE10ANPC1 | |
| SCHEMBL6795429 | 0.83 | GRIN1 (0.59) | GRIN2BGRIN1GAAPKMTSHR | |
| SCHEMBL6542830 | 0.82 | GAA (0.60) | GRIN2BGRIN1GAAHTR6PKM | |
| SCHEMBL7692083 | 0.82 | GRIN2B (0.59) | GRIN2BGRIN1GAAHTR6PKM | |
| Hydrochloric Acid SCHEMBL10410762 | 0.82 | GRIN1 (0.73) | GRIN2BGRIN1GAA | |
| Hydrochloric Acid SCHEMBL6791084 | 0.81 | GRIN1 (0.58) | GRIN2BGRIN1GAAPKMTSHR | |
| SCHEMBL3790024 | 0.81 | GAA (0.58) | GRIN2BGRIN1GAAHTR6PKM | |
| SCHEMBL9533100 | 0.80 | GRIN1 (0.55) | GRIN2BGRIN1GAATSHRPDE10A | |
| SCHEMBL8816584 | 0.79 | GAA (0.57) | GRIN2BGRIN1GAAHTR6PKM | |
| SCHEMBL6367925 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993002087-A1 | GALLIUM (III) COMPLEXES, PROCESS FOR THEIR OBTENTION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | LES LABORATOIRES MERAM (FR) | 1993-02-04 | — | — | WO | claimed |
| EP-0178413-A1 | Benzimidazoles | BEECHAM GROUP PLC (GB) | 1986-04-23 | — | — | EP | claimed |
| WO-1993002087-A1 | GALLIUM (III) COMPLEXES, PROCESS FOR THEIR OBTENTION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | LES LABORATOIRES MERAM (FR) | 1993-02-04 | — | — | WO | disclosed |
| US-4925853-A | Antiinflammatory, antiallergens, antiulcer agents | BEECHAM GROUP PLC (GB) | 1990-05-15 | — | — | US | disclosed |
| EP-0310808-A1 | Curable compositions and corrosion resistant coatings prepared therefrom | AMERICAN CYANAMID COMPANY (US) | 1989-04-12 | — | — | EP | disclosed |
| US-4778728-A | AMINE-REACTIVE POLYMER OF (METH)ACRYLAMAIDOGLYCOLATE, POLYFUNCTIONAL AMINE CROSSLINKER, BENZOTRIAZOLE OR A DIPYRIDYL | AMERICAN CYANAMID COMPANY (US) | 1988-10-18 | — | — | US | disclosed |
| EP-0178413-A1 | Benzimidazoles | BEECHAM GROUP PLC (GB) | 1986-04-23 | — | — | EP | disclosed |