Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 3/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | MPO | P05164 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | PTPRA | P18433 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.46 |
| ▸ | CDK2 | P24941 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1342863 | 0.86 | TACR1 (0.74) | TACR1KDM4EKMT2ALMNAMEN1 | |
| SCHEMBL7743113 | 0.84 | TACR1 (0.66) | TACR1KDM4EKMT2ALMNAMEN1 | |
| SCHEMBL27744048 | 0.83 | KMT2A (0.54) | TACR1KDM4EKMT2ALMNAMEN1 | |
| SCHEMBL1653790 | 0.82 | KMT2A (0.53) | TACR1KDM4EKMT2ALMNAMEN1 | |
| SCHEMBL8740387 | 0.82 | KMT2A (0.53) | TACR1KDM4EKMT2ALMNAMEN1 | |
| SCHEMBL18000223 | 0.82 | MAPT (0.64) | TACR1KDM4EKMT2ALMNAMEN1 | |
| Ammonia Solution, Strong SCHEMBL5385746 | 0.81 | KMT2A (0.52) | TACR1KDM4EKMT2ALMNAMEN1 | |
| SCHEMBL5320005 | 0.81 | MAPT (0.60) | TACR1KDM4EKMT2ALMNAMEN1 | |
| SCHEMBL8025702 | 0.80 | TACR1 (0.77) | TACR1KDM4EKMT2ALMNAMEN1 | |
| SCHEMBL1167914 | 0.80 | TACR1 (0.77) | TACR1KDM4EKMT2ALMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993001169-A2 | AROMATIC COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USE IN THERAPY | MERCK SHARP & DOHME LIMITED (GB) | 1993-01-21 | — | — | WO | disclosed |