Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | MPO | P05164 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | BLM | P54132 | 1/20 | 0.59 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.59 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.59 |
| ▸ | TACR1 | P25103 | 2/20 | 0.53 |
| ▸ | PTPRA | P18433 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | APAF1 | O14727 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18000223 | 0.82 | MAPT (0.64) | KDM4EMAPTMEN1KMT2ALMNA | |
| SCHEMBL27645851 | 0.80 | KMT2A (0.73) | KDM4EMAPTMEN1KMT2ALMNA | |
| SCHEMBL23723484 | 0.80 | MAPT (0.76) | KDM4EMAPTMEN1KMT2ALMNA | |
| SCHEMBL29472033 | 0.80 | MAPT (0.76) | KDM4EMAPTMEN1KMT2ALMNA | |
| SCHEMBL16007279 | 0.79 | KDM4E (0.67) | KDM4EMAPTMEN1KMT2ALMNA | |
| SCHEMBL7775115 | 0.79 | KDM4E (0.67) | KDM4EMAPTMEN1KMT2ALMNA | |
| SCHEMBL28982974 | 0.79 | MAPT (0.67) | KDM4EMAPTMEN1KMT2ALMNA | |
| Tryptophan SCHEMBL8586730 | 0.79 | KMT2A (0.84) | KDM4EMAPTMEN1KMT2ALMNA | |
| Tryptophan SCHEMBL8586731 | 0.79 | KMT2A (0.84) | KDM4EMAPTMEN1KMT2ALMNA | |
| Dl-Tryptophan SCHEMBL8586728 | 0.79 | KMT2A (0.84) | KDM4EMAPTMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993001169-A2 | AROMATIC COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USE IN THERAPY | MERCK SHARP & DOHME LIMITED (GB) | 1993-01-21 | — | — | WO | disclosed |