Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | BRD4 | O60885 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | EGFR | P00533 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1545310 | 0.88 | EGFR (0.64) | MAOBSMN1; SMN2HPGDNPC1RAB9A | |
| SCHEMBL29803481 | 0.88 | EGFR (0.64) | MAOBSMN1; SMN2HPGDNPC1RAB9A | |
| SCHEMBL3960943 | 0.88 | NR4A2 (0.58) | SMN1; SMN2HPGDNPC1RAB9AMRGPRX4 | |
| SCHEMBL3123036 | 0.88 | MAOB (0.64) | MAOBSMN1; SMN2HPGDNPC1RAB9A | |
| SCHEMBL21588079 | 0.85 | HPGD (0.68) | SMN1; SMN2HPGDNPC1RAB9AL3MBTL1 | |
| SCHEMBL22015271 | 0.84 | LMNA (0.62) | SMN1; SMN2HPGDNPC1RAB9AMAPT | |
| SCHEMBL31025721 | 0.84 | NPC1 (0.75) | MAOBSMN1; SMN2HPGDNPC1RAB9A | |
| SCHEMBL22325324 | 0.84 | MAOB (0.59) | MAOBSMN1; SMN2HPGDNPC1RAB9A | |
| SCHEMBL9236564 | 0.84 | SMPD1 (0.73) | MAOBSMN1; SMN2HPGDNPC1RAB9A | |
| SCHEMBL340620 | 0.84 | NPC1 (0.75) | MAOBSMN1; SMN2HPGDNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109232251-A | 3, 4-Dihydroxyacetophenone derivative, preparation method, application and pharmaceutical composition | 潍坊医学院 | 2019-01-18 | — | — | CN | claimed |
| CN-109232251-B | Caryopyrone derivatives, preparation method, application and pharmaceutical composition thereof | 潍坊医学院 | 2022-03-25 | — | — | CN | disclosed |
| CN-109232251-B | Caryopyrone derivatives, preparation method, application and pharmaceutical composition thereof | 潍坊医学院 | 2022-03-25 | — | — | CN | disclosed |
| CN-109232251-A | 3, 4-Dihydroxyacetophenone derivative, preparation method, application and pharmaceutical composition | 潍坊医学院 | 2019-01-18 | — | — | CN | disclosed |
| WO-1993014751-A1 | PHARMACEUTICAL COMPOSITIONS CONTAINING AS ACTIVE PRINCIPLE ASSOCIATIONS OF VANADIUM AND/OR NIOBIUM WITH PYROCATECHOL DERIVATIVES | I.R.2.M. (FR) | 1993-08-05 | — | — | WO | disclosed |
| EP-0167204-B1 | METHOD FOR IMPROVING THE ABSORPTION AND EFFECTIVENESS OF A CATECHOLAMINE COMPOUND | SIMES S.p.A. Società Italiana Medicinali e Sintetici (IT) | 1989-09-27 | — | — | EP | disclosed |
| US-4673671-A | CONVERSION TO MONO O-PHOSPHATE ESTER | SIMES SOCIETA ITALIANA MEDICINALI E SINTETICI S.P.A. (IT) | 1987-06-16 | — | — | US | disclosed |
| EP-0167204-A1 | Method for improving the absorption and effectiveness of a catecholamine compound | SIMES S.p.A. Società Italiana Medicinali e Sintetici (IT) | 1986-01-08 | — | — | EP | disclosed |