SCHEMBL9540606

SCHEMBL9540606

O=[N+]([O-])c1cccc(S(=O)(=O)O)c1.O=[N+]([O-])c1cccc(S(=O)(=O)O)c1.c1ccc(CNCc2ccc(CNCc3ccccc3)cc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 1/20 0.56
CA2 P00918 3/20 0.52
CA1 P00915 2/20 0.52
MMP1 P03956 1/20 0.52
MMP2 P08253 1/20 0.52
MMP9 P14780 1/20 0.52
MMP8 P22894 1/20 0.52
MMP13 P45452 1/20 0.52
KMT2A Q03164 3/20 0.51
HTT P42858 2/20 0.51
GAA P10253 1/20 0.51
MEN1 O00255 2/20 0.51
ALDH1A1 P00352 3/20 0.51
AR P10275 1/20 0.49
CA5A P35218 1/20 0.49
DDX3X O00571 1/20 0.48
LMNA P02545 1/20 0.47
HPGD P15428 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
N-Benzylmethylamine SCHEMBL9727027 0.88 CYP19A1 (0.55) CYP19A1CA2CA1MMP1MMP2
Diphenylmethane SCHEMBL9101946 0.86 KMT2A (0.57) CYP19A1CA2CA1MMP1MMP2
Benzylamine SCHEMBL9450916 0.85 CA2 (0.56) CYP19A1CA2CA1MMP1MMP2
Benzylamine SCHEMBL9450914 0.85 CA2 (0.56) CYP19A1CA2CA1MMP1MMP2
Benzene SCHEMBL27935914 0.84 KMT2A (0.70) CYP19A1CA2CA1MMP1MMP2
SCHEMBL33351 0.83 KMT2A (0.72) CYP19A1CA2CA1MMP1MMP2
SCHEMBL9471995 0.83 KMT2A (0.72) CYP19A1CA2CA1MMP1MMP2
SCHEMBL6525363 0.83 KMT2A (0.72) CYP19A1CA2CA1MMP1MMP2
SCHEMBL33350 0.83 KMT2A (0.72) CYP19A1CA2CA1MMP1MMP2
SCHEMBL30482083 0.81 TSHR (0.59) CYP19A1KMT2AMEN1ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1993002041-A1 ESTER-CONTAINING QUATERNARY AMMONIUM SALTS EASTMAN KODAK COMPANY (US) 1993-02-04 WO disclosed