Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 2/20 | 0.46 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.46 |
| ▸ | SLC33A1 | O00400 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9150664 | 0.93 | AGTR1 (0.46) | AGTR1AGTR2SLC33A1 | |
| SCHEMBL9155332 | 0.90 | AGTR1 (0.41) | AGTR1AGTR2 | |
| SCHEMBL9152704 | 0.89 | AGTR1 (0.47) | AGTR1 | |
| SCHEMBL9152320 | 0.89 | AGTR1 (0.43) | AGTR1AGTR2 | |
| SCHEMBL9151719 | 0.86 | AGTR1 (0.39) | AGTR1 | |
| SCHEMBL9540406 | 0.86 | — | — | |
| SCHEMBL9154568 | 0.85 | AGTR1 (0.42) | AGTR1 | |
| SCHEMBL9151511 | 0.85 | — | — | |
| SCHEMBL9151481 | 0.84 | AGTR1 (0.47) | AGTR1AGTR2 | |
| SCHEMBL9153686 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993005025-A1 | C-LINKED PYRAZOLE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1993-03-18 | — | — | WO | disclosed |
| EP-0446062-A1 | C-Linked pyrazole derivatives | GLAXO GROUP LIMITED (GB) | 1991-09-11 | — | — | EP | disclosed |