Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.51 |
| ▸ | PLA2G4B | P0C869 | 4/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29242919 | 1.00 | CETP (0.52) | CETPKMT2AMEN1EPHX2PLA2G4B | |
| SCHEMBL18800110 | 0.97 | EPHX2 (0.51) | CETPKMT2AMEN1EPHX2PLA2G4B | |
| SCHEMBL25616458 | 0.95 | L3MBTL1 (0.50) | CETPKMT2AMEN1EPHX2PLA2G4B | |
| SCHEMBL25118437 | 0.94 | CETP (0.52) | CETPKMT2AMEN1EPHX2PLA2G4B | |
| SCHEMBL19032713 | 0.92 | EPHX2 (0.57) | EPHX2L3MBTL1TDP1TSHRMAPT | |
| SCHEMBL10081325 | 0.92 | EPHX2 (0.57) | EPHX2L3MBTL1TDP1TSHRMAPT | |
| SCHEMBL25269510 | 0.92 | EPHX2 (0.57) | EPHX2L3MBTL1TDP1TSHRMAPT | |
| SCHEMBL19127414 | 0.88 | CETP (0.50) | CETPKMT2AMEN1EPHX2L3MBTL1 | |
| SCHEMBL19734678 | 0.88 | TSHR (0.50) | CETPKMT2AMEN1EPHX2L3MBTL1 | |
| SCHEMBL11601193 | 0.88 | EPHX2 (0.50) | EPHX2L3MBTL1TDP1ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993001196-A1 | KETOALKYLGLYCEROPHOSPHOLIPIDS HAVING ANTITUMOR AND ANTI-PLATELET AGGREGATION ACTIVITIES, PROCESSES FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS THEREFROM | LABORATORIOS MENARINI S.A. (ES) | 1993-01-21 | — | — | WO | disclosed |