Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 2/20 | 0.46 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.45 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.45 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.45 |
| ▸ | BRS3 | P32247 | 2/20 | 0.44 |
| ▸ | RARB | P10826 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8979770 | 0.90 | AGTR1 (0.56) | AGTR1AGTR2BRS3 | |
| SCHEMBL9196825 | 0.82 | AGTR1 (0.49) | AGTR1AGTR2 | |
| SCHEMBL8979766 | 0.81 | AGTR1 (0.51) | AGTR1AGTR2BRS3 | |
| SCHEMBL9202144 | 0.80 | AGTR1 (0.46) | AGTR1AGTR2FOLH1BRS3 | |
| SCHEMBL9199769 | 0.77 | CNR1 (0.39) | AGTR1AGTR2 | |
| SCHEMBL8504803 | 0.77 | DHODH (0.51) | AGTR1AGTR2FOLH1BRS3 | |
| SCHEMBL9202367 | 0.77 | AGTR1 (0.44) | AGTR1AGTR2FOLH1BRS3 | |
| SCHEMBL3737185 | 0.76 | FOLH1 (0.63) | PTPN11AGTR1AGTR2FOLH1BRS3 | |
| SCHEMBL8979762 | 0.76 | AGTR1 (0.47) | AGTR1AGTR2BRS3 | |
| SCHEMBL1226948 | 0.74 | AGTR1 (0.54) | AGTR1AGTR2BRS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993003018-A1 | COMPOUNDS HAVING ANGIOTENSINE II ANTAGONISTIC ACTIVITY | ISTITUTO LUSO FARMACO D'ITALIA S.P.A. (IT) | 1993-02-18 | — | — | WO | disclosed |