Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | IKBKB | O14920 | 1/20 | 0.40 |
| ▸ | CHUK | O15111 | 1/20 | 0.40 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27407297 | 0.85 | KDM4E (0.51) | TP53KDM4EMAPTHPGDALDH1A1 | |
| SCHEMBL9541050 | 0.83 | TP53 (0.43) | TP53KDM4EMAPTHPGDALDH1A1 | |
| SCHEMBL9541069 | 0.79 | KDM4E (0.49) | TP53KDM4EMAPTHPGDALDH1A1 | |
| SCHEMBL9540850 | 0.78 | TP53 (0.43) | TP53KDM4EMAPTHPGDALDH1A1 | |
| SCHEMBL9539884 | 0.78 | KDM4E (0.40) | TP53KDM4EMAPTHPGDALDH1A1 | |
| SCHEMBL259246 | 0.74 | HTT (0.58) | TP53KDM4EMAPTHPGDALDH1A1 | |
| SCHEMBL9541072 | 0.72 | KDM4E (0.50) | TP53KDM4EMAPTHPGDALDH1A1 | |
| SCHEMBL7541097 | 0.71 | KDM4E (0.59) | TP53KDM4EMAPTHPGDALDH1A1 | |
| SCHEMBL259035 | 0.70 | ALDH1A1 (0.54) | TP53KDM4EALDH1A1RAB9AIKBKB | |
| SCHEMBL7539997 | 0.70 | KDM4E (0.50) | TP53KDM4EALDH1A1NPSR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993013664-A2 | BIHETEROCYCLIC FUNGICIDAL COMPOUNDS | SCHERING AGROCHEMICALS LIMITED (GB) | 1993-07-22 | — | — | WO | disclosed |