Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.54 |
| ▸ | RAB9A | P51151 | 6/20 | 0.54 |
| ▸ | HPGD | P15428 | 6/20 | 0.54 |
| ▸ | NPC1 | O15118 | 5/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | CASP1 | P29466 | 1/20 | 0.54 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.54 |
| ▸ | CASP7 | P55210 | 1/20 | 0.54 |
| ▸ | FYN | P06241 | 7/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9538674 | 0.81 | KDM4E (0.39) | KDM4EALDH1A1RAB9AHPGDNPC1 | |
| SCHEMBL2815100 | 0.74 | ALDH1A1 (0.41) | KDM4EALDH1A1RAB9AHPGDHSD17B10 | |
| SCHEMBL2818740 | 0.73 | ADORA2A (0.58) | KDM4EALDH1A1RAB9AHPGDNPC1 | |
| SCHEMBL9540820 | 0.73 | ADORA2A (0.58) | KDM4EALDH1A1RAB9AHPGDNPC1 | |
| SCHEMBL2816945 | 0.71 | FYN (0.50) | RAB9AHSD17B10SMN1; SMN2FYNLMNA | |
| SCHEMBL9542204 | 0.71 | BCHE (0.49) | KDM4EALDH1A1HPGDGAAMAPT | |
| SCHEMBL9539492 | 0.71 | FGFR1 (0.46) | KDM4EALDH1A1RAB9AHPGDNPC1 | |
| SCHEMBL2815669 | 0.71 | KMT2A (0.44) | KDM4EALDH1A1RAB9AHPGDNPC1 | |
| SCHEMBL16328032 | 0.71 | ALDH1A1 (0.46) | KDM4EALDH1A1HPGDHSD17B10SMN1; SMN2 | |
| SCHEMBL708998 | 0.71 | NPC1 (1.00) | KDM4EALDH1A1RAB9AHPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993004066-A1 | CERTAIN IMIDAZOQUINOXALINOLS; A NEW CLASS OF GABA BRAIN RECEPTOR LIGANDS | NEUROGEN CORPORATION (US) | 1993-03-04 | — | — | WO | claimed |