Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | IKBKB | O14920 | 2/20 | 0.45 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9542517 | 0.85 | MAPT (0.51) | MAPTNPC1RAB9AALDH1A1NPSR1 | |
| SCHEMBL16475084 | 0.82 | KDM4E (0.48) | MAPTNPC1RAB9AALDH1A1NPSR1 | |
| SCHEMBL9540913 | 0.76 | ALDH1A1 (0.45) | MAPTNPC1RAB9AALDH1A1NPSR1 | |
| SCHEMBL16479434 | 0.72 | KDM4E (0.46) | MAPTNPC1RAB9AALDH1A1NPSR1 | |
| SCHEMBL16475089 | 0.72 | KDM4E (0.46) | MAPTNPC1RAB9AALDH1A1NPSR1 | |
| SCHEMBL9540895 | 0.70 | MAPT (0.40) | MAPTNPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL16475088 | 0.68 | KDM4E (0.61) | MAPTNPC1RAB9AALDH1A1NPSR1 | |
| SCHEMBL9542502 | 0.68 | ALDH1A1 (0.38) | MAPTNPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL9541204 | 0.67 | NSD2 (0.42) | MAPTALDH1A1KDM4EHPGDKMT2A | |
| SCHEMBL4126822 | 0.66 | IKBKB (0.52) | MAPTNPC1RAB9AALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993013664-A2 | BIHETEROCYCLIC FUNGICIDAL COMPOUNDS | SCHERING AGROCHEMICALS LIMITED (GB) | 1993-07-22 | — | — | WO | disclosed |