Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | METAP2 | P50579 | 2/20 | 0.44 |
| ▸ | METAP1 | P53582 | 2/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | MPI | P34949 | 1/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.40 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | IKBKB | O14920 | 1/20 | 0.39 |
| ▸ | CHUK | O15111 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2176528 | 0.77 | AXL (0.42) | KDM4EHSP90AA1LMNAMAPTL3MBTL1 | |
| SCHEMBL30489898 | 0.77 | AXL (0.42) | KDM4EHSP90AA1LMNAMAPTL3MBTL1 | |
| SCHEMBL12334 | 0.75 | NPC1 (0.43) | KDM4EHSP90AA1LMNAMAPTL3MBTL1 | |
| SCHEMBL2713045 | 0.75 | HSP90AA1 (0.42) | KDM4EHSP90AA1LMNAMAPTHTT | |
| SCHEMBL30338424 | 0.75 | HSP90AA1 (0.42) | KDM4EHSP90AA1LMNAMAPTHTT | |
| SCHEMBL31252939 | 0.75 | KDM4E (0.40) | KDM4EHSP90AA1LMNAMAPTMETAP2 | |
| SCHEMBL3971484 | 0.75 | KDM4E (0.40) | KDM4EHSP90AA1LMNAMAPTMETAP2 | |
| SCHEMBL5279895 | 0.75 | KDM4E (0.38) | KDM4EHSP90AA1LMNAMAPTL3MBTL1 | |
| SCHEMBL22270961 | 0.75 | KDM4E (0.39) | KDM4EHSP90AA1LMNAMAPTMETAP2 | |
| SCHEMBL9754157 | 0.73 | KDM4E (0.48) | KDM4ELMNAMAPTL3MBTL1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993013664-A2 | BIHETEROCYCLIC FUNGICIDAL COMPOUNDS | SCHERING AGROCHEMICALS LIMITED (GB) | 1993-07-22 | — | — | WO | claimed |
| WO-1993013664-A2 | BIHETEROCYCLIC FUNGICIDAL COMPOUNDS | SCHERING AGROCHEMICALS LIMITED (GB) | 1993-07-22 | — | — | WO | disclosed |