Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 5/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | CASP6 | P55212 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MGAM | O43451 | 1/20 | 0.42 |
| ▸ | SI | P14410 | 1/20 | 0.42 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19323400 | 0.80 | POLB (0.69) | ALDH1A1RAB9APOLBTDP1CASP6 | |
| SCHEMBL19324112 | 0.80 | POLB (0.69) | ALDH1A1RAB9APOLBTDP1CASP6 | |
| SCHEMBL27948552 | 0.80 | POLB (0.69) | ALDH1A1RAB9APOLBTDP1CASP6 | |
| SCHEMBL19318637 | 0.80 | POLB (0.69) | ALDH1A1RAB9APOLBTDP1CASP6 | |
| SCHEMBL19318634 | 0.80 | POLB (0.69) | ALDH1A1RAB9APOLBTDP1CASP6 | |
| SCHEMBL29307701 | 0.80 | POLB (0.69) | ALDH1A1RAB9APOLBTDP1CASP6 | |
| SCHEMBL5837751 | 0.80 | POLB (0.69) | ALDH1A1RAB9APOLBTDP1CASP6 | |
| SCHEMBL5837756 | 0.80 | POLB (0.69) | ALDH1A1RAB9APOLBTDP1CASP6 | |
| SCHEMBL7594331 | 0.80 | POLB (0.69) | ALDH1A1RAB9APOLBTDP1CASP6 | |
| SCHEMBL20867585 | 0.78 | POLB (0.51) | ALDH1A1RAB9APOLBTDP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993014062-A1 | ANTHELMINTIC β-KETOAMIDES | THE UPJOHN COMPANY (US) | 1993-07-22 | — | — | WO | claimed |
| WO-1993014062-A1 | ANTHELMINTIC β-KETOAMIDES | THE UPJOHN COMPANY (US) | 1993-07-22 | — | — | WO | disclosed |