Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 2/20 | 0.58 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | PARP1 | P09874 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | HTR2C | P28335 | 1/20 | 0.48 |
| ▸ | HTR7 | P34969 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.48 |
| ▸ | HTR2B | P41595 | 1/20 | 0.48 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.46 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.46 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.46 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.46 |
| ▸ | METAP1 | P53582 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29773995 | 0.89 | NPC1 (0.64) | SRD5A2SRD5A1NPC1MAPTRAB9A | |
| SCHEMBL11808856 | 0.86 | SRD5A2 (0.62) | SRD5A2SRD5A1NPC1MAPTRAB9A | |
| SCHEMBL6536471 | 0.84 | SRD5A2 (0.81) | SRD5A2SRD5A1NPC1MAPTRAB9A | |
| SCHEMBL5048102 | 0.83 | RAB9A (0.79) | SRD5A2SRD5A1NPC1MAPTRAB9A | |
| SCHEMBL29773950 | 0.81 | SRD5A2 (0.72) | SRD5A2SRD5A1NPC1MAPTRAB9A | |
| SCHEMBL1700638 | 0.81 | SRD5A2 (0.72) | SRD5A2SRD5A1NPC1MAPTRAB9A | |
| SCHEMBL14690867 | 0.80 | SRD5A2 (0.55) | SRD5A2SRD5A1NPC1MAPTRAB9A | |
| SCHEMBL14691549 | 0.80 | SRD5A2 (0.55) | SRD5A2SRD5A1NPC1MAPTRAB9A | |
| Methyl Carbamate SCHEMBL28827531 | 0.79 | SLC1A3 (0.49) | SRD5A2SRD5A1NPC1MAPTRAB9A | |
| SCHEMBL29376113 | 0.79 | METAP1 (0.57) | SRD5A2SRD5A1NPC1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993014062-A1 | ANTHELMINTIC β-KETOAMIDES | THE UPJOHN COMPANY (US) | 1993-07-22 | — | — | WO | claimed |
| WO-1993014062-A1 | ANTHELMINTIC β-KETOAMIDES | THE UPJOHN COMPANY (US) | 1993-07-22 | — | — | WO | disclosed |