Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 9/20 | 0.58 |
| ▸ | BCHE | P06276 | 8/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9539725 | 0.87 | ACHE (0.70) | ACHEBCHEKDM4EALDH1A1HPGD | |
| SCHEMBL9538390 | 0.87 | BCHE (0.73) | ACHEBCHE | |
| SCHEMBL9541181 | 0.85 | BCHE (0.42) | ACHEBCHEKDM4EALDH1A1HPGD | |
| Salicylic Acid SCHEMBL9541012 | 0.84 | KDM4E (0.55) | ACHEBCHEKDM4EALDH1A1HPGD | |
| SCHEMBL8863165 | 0.80 | ACHE (0.51) | ACHEBCHEKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL8863164 | 0.80 | ACHE (0.51) | ACHEBCHEKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL9006729 | 0.80 | ACHE (0.51) | ACHEBCHEKDM4EALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL9537532 | 0.79 | ACHE (0.50) | ACHEBCHEKDM4EHIF1A | |
| SCHEMBL8827828 | 0.77 | KDM4E (0.67) | KDM4EALDH1A1SMN1; SMN2HIF1AHSD17B10 | |
| SCHEMBL9538917 | 0.77 | KDM4E (0.67) | KDM4EALDH1A1SMN1; SMN2HIF1AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5187165-A | Eseroline derivatives; cholinergic agents; antidepressants | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1993-02-16 | — | — | US | disclosed |