Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 1/20 | 0.73 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.65 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.65 |
| ▸ | MMP1 | P03956 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.56 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.56 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.56 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.56 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.56 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.56 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.56 |
| ▸ | GSK3B | P49841 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6160043 | 0.95 | HDAC8 (0.72) | PDE4BHDAC8HDAC1MMP1MAPT | |
| SCHEMBL4082864 | 0.91 | PDE4B (0.86) | PDE4BHDAC8HDAC1MMP1MAPT | |
| SCHEMBL1108994 | 0.89 | MMP1 (0.70) | PDE4BHDAC8HDAC1MMP1MAPT | |
| SCHEMBL3171960 | 0.87 | PDE4B (0.79) | PDE4BHDAC8HDAC1MMP1MAPT | |
| SCHEMBL5269091 | 0.85 | PDE4B (0.67) | PDE4BHDAC8HDAC1MMP1MAPT | |
| SCHEMBL11281722 | 0.84 | PDE4B (0.70) | PDE4BHDAC8HDAC1MMP1MAPT | |
| SCHEMBL7995333 | 0.84 | PDE4B (0.75) | PDE4BHDAC8HDAC1MMP1MAPT | |
| SCHEMBL99448 | 0.84 | PDE4B (1.00) | PDE4BHDAC8HDAC1MMP1MAPT | |
| SCHEMBL28440147 | 0.84 | PDE4B (0.56) | PDE4BHDAC8HDAC1MAPTKMT2A | |
| SCHEMBL14960046 | 0.84 | PDE4B (0.75) | PDE4BHDAC8HDAC1MMP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5170696-A | — | — | None | — | — | JP | disclosed |
| JP-H05170696-A | BIS(4-ALKOXYPHENYL)ETHYLENE DERIVATIVE | HOKURIKU SEIYAKU CO LTD | 1993-07-09 | — | — | JP | disclosed |