SCHEMBL9541294

SCHEMBL9541294

CC(C)OC(=O)c1sc2cnccc2c1O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.52
HPGD P15428 4/20 0.52
KDM4E B2RXH2 3/20 0.52
HTT P42858 2/20 0.52
GLA P06280 1/20 0.52
GAA P10253 1/20 0.52
CASP1 P29466 1/20 0.52
CASP7 P55210 1/20 0.52
NCOA1 Q15788 1/20 0.52
HSD17B10 Q99714 1/20 0.52
RCE1 Q9Y256 1/20 0.52
NCOA3 Q9Y6Q9 1/20 0.52
MEN1 O00255 2/20 0.39
RAB9A P51151 2/20 0.39
KMT2A Q03164 2/20 0.39
RPS6KB1 P23443 1/20 0.39
CDK2 P24941 1/20 0.39
MAPKAPK2 P49137 1/20 0.39
GSK3B P49841 1/20 0.39
RPS6KA3 P51812 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4722269 0.85 ALDH1A1 (0.73) ALDH1A1HPGDKDM4EHTTGLA
SCHEMBL4858672 0.84 ALDH1A1 (0.72) ALDH1A1HPGDKDM4EHTTGLA
SCHEMBL30555073 0.81 KDM4E (0.52) ALDH1A1HPGDKDM4EHTTGLA
SCHEMBL1218547 0.81 KDM4E (0.52) ALDH1A1HPGDKDM4EHTTGLA
SCHEMBL21950008 0.77 ALDH1A1 (0.50) ALDH1A1HPGDKDM4EHTTGLA
SCHEMBL4856080 0.72 ALDH1A1 (0.59) ALDH1A1HPGDKDM4EHTTGLA
SCHEMBL9540885 0.72 KDM4E (0.47) ALDH1A1HPGDKDM4EGAAMEN1
SCHEMBL1813746 0.70 ALDH1A1 (0.72) ALDH1A1HPGDKDM4EHTTGLA
SCHEMBL1215521 0.69 CDC7 (0.50) ALDH1A1HPGDKDM4EHTTGLA
SCHEMBL24455354 0.69 RPS6KB1 (0.49) ALDH1A1HPGDKDM4EHTTGLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1993013664-A2 BIHETEROCYCLIC FUNGICIDAL COMPOUNDS SCHERING AGROCHEMICALS LIMITED (GB) 1993-07-22 WO disclosed