Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.33 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | CPA1 | P15085 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9541472 | 0.83 | TSHR (0.41) | TSHRMAPTTDP1USP2LMNA | |
| SCHEMBL7686788 | 0.83 | TSHR (0.41) | TSHRMAPTTDP1USP2LMNA | |
| SCHEMBL8212975 | 0.82 | TSHR (0.39) | TSHRGRIK1GRIK2MAPTTDP1 | |
| SCHEMBL8221276 | 0.82 | TSHR (0.39) | TSHRGRIK1GRIK2MAPTTDP1 | |
| SCHEMBL28773870 | 0.82 | TSHR (0.39) | TSHRGRIK1GRIK2MAPTTDP1 | |
| SCHEMBL28725161 | 0.80 | TSHR (0.35) | TSHRGRIK1GRIK2MAPTCYP2C19 | |
| SCHEMBL319704 | 0.79 | MAPT (0.39) | TSHRMAPTCYP2C19 | |
| SCHEMBL28725124 | 0.76 | GAA (0.52) | TSHRMAPTTDP1LMNASMN1; SMN2 | |
| SCHEMBL8239347 | 0.76 | TSHR (0.33) | TSHRGRIK1GRIK2SMN1; SMN2 | |
| SCHEMBL3508923 | 0.75 | TYR (0.40) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993011669-A1 | USE OF 3-PHENYLURACIL DERIVATIVES FOR THE DESICCATION AND ABSCISSION OF PLANT PARTS | BASF AKTIENGESELLSCHAFT (DE) | 1993-06-24 | — | — | WO | disclosed |