Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT3 | O60678 | 1/20 | 0.36 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.36 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.36 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.36 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5858575 | 0.86 | PRMT3 (0.39) | PRMT3CARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL24542710 | 0.81 | — | — | |
| SCHEMBL25699137 | 0.81 | — | — | |
| SCHEMBL17921493 | 0.80 | PRMT3 (0.36) | PRMT3CARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL19786168 | 0.78 | SLC6A4 (0.32) | HTR2AHRH1SLC6A4 | |
| SCHEMBL22129892 | 0.78 | PRMT3 (0.40) | PRMT3CARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL5608082 | 0.78 | PRMT3 (0.40) | PRMT3CARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL5694829 | 0.78 | MAPT (0.38) | PRMT3CARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL19445841 | 0.78 | SLC6A4 (0.37) | SLC6A4 | |
| SCHEMBL272657 | 0.76 | MAPT (0.42) | PRMT3CARM1PRMT6PRMT1PRMT8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024019995-A1 | QUINOXALINEDIONE AND PYRIDO [2, 3-B]PYRAZINE-2, 3-DIONE B CELL LYMPHOMA 6 (BCL6) DEGRADERS AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2024-01-25 | — | — | WO | disclosed |
| EP-2928581-B1 | PROCESS FOR ABSORPTION OF CO2 FROM A GAS MIXTURE USING AN AQUEOUS SOLUTION OF A DIAMINE | EVONIK DEGUSSA GMBH (DE) | 2016-10-19 | — | — | EP | disclosed |
| US-20150321139-A1 | PROCESS FOR ABSORPTION OF CO2 FROM A GAS MIXTURE USING AN AQUEOUS SOLUTION OF A DIAMINE | EVONIK INDUSTRIES AG (DE) | 2015-11-12 | — | — | US | disclosed |
| EP-1518855-B1 | DIAMINOPYRIMIDINECARBOXA MIDE DERIVATIVE | ASTELLAS PHARMA INC (JP) | 2011-10-26 | — | — | EP | disclosed |
| US-5270310-A | N-aminoalkyl amide inhibitors of protein kinase C | SPHINX PHARMACEUTICALS CORPORATION (US) | 1993-12-14 | — | — | US | disclosed |
| WO-1993011758-A1 | N-AMINOALKYL AMIDE INHIBITORS OF PROTEIN KINASE C | SPHINX PHARMACEUTICALS CORPORATION (US) | 1993-06-24 | — | — | WO | disclosed |