Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 6/20 | 0.46 |
| ▸ | DRD3 | P35462 | 6/20 | 0.46 |
| ▸ | DRD4 | P21917 | 4/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 11/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8765828 | 1.00 | DRD2 (0.46) | DRD2DRD3DRD4ADRB3ADRB1 | |
| SCHEMBL8765981 | 1.00 | DRD2 (0.46) | DRD2DRD3DRD4ADRB3ADRB1 | |
| SCHEMBL5145507 | 0.88 | ADRB3 (0.46) | DRD2DRD3DRD4ADRB3ADRB1 | |
| Hydrochloric Acid SCHEMBL5143780 | 0.88 | ADRB3 (0.46) | DRD2DRD3DRD4ADRB3ADRB1 | |
| SCHEMBL8765168 | 0.88 | DRD2 (0.46) | DRD2DRD3DRD4MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL8765098 | 0.83 | ADRB3 (0.52) | ADRB3ADRB1 | |
| Hydrochloric Acid SCHEMBL8765887 | 0.83 | ADRB3 (0.47) | ADRB3ADRB1 | |
| Hydrochloric Acid SCHEMBL8765890 | 0.83 | ADRB3 (0.47) | ADRB3ADRB1 | |
| Hydrochloric Acid SCHEMBL8765093 | 0.83 | ADRB3 (0.52) | ADRB3ADRB1 | |
| SCHEMBL9542017 | 0.83 | ADRB3 (0.46) | ADRB3ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993015041-A1 | ETHANOLAMINE DERIVATIVES HAVING SYMPATHOMIMETIC AND ANTI-POLLAKIURIA ACTIVITIES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-08-05 | — | — | WO | disclosed |