Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 20/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2183243 | 0.89 | HSP90AA1 (0.55) | HSP90AA1 | |
| SCHEMBL949653 | 0.87 | HSP90AA1 (0.56) | HSP90AA1 | |
| SCHEMBL1395321 | 0.86 | HSP90AA1 (0.74) | HSP90AA1 | |
| SCHEMBL1395324 | 0.86 | HSP90AA1 (0.74) | HSP90AA1 | |
| SCHEMBL951938 | 0.86 | HSP90AA1 (0.74) | HSP90AA1 | |
| SCHEMBL949717 | 0.85 | HSP90AA1 (0.76) | HSP90AA1 | |
| SCHEMBL420426 | 0.84 | HSP90AA1 (0.75) | HSP90AA1 | |
| SCHEMBL949997 | 0.84 | HSP90AA1 (0.75) | HSP90AA1 | |
| SCHEMBL420425 | 0.84 | HSP90AA1 (0.75) | HSP90AA1 | |
| SCHEMBL951332 | 0.80 | BIRC5 (0.37) | HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011004132-A1 | NOVEL HSP90-INHIBITING INDOLE DERIVATIVES, COMPOSITIONS CONTAINING SAID DERIVATIVES, AND USE THEREOF | SANOFI-AVENTIS (FR) | 2011-01-13 | — | — | WO | disclosed |