Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | TP53 | P04637 | 3/20 | 0.45 |
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8561030 | 0.93 | MAPT (0.56) | MAPTSMN1; SMN2TP53THRBPDE4B | |
| Hydrochloric Acid SCHEMBL8625846 | 0.93 | MAPT (0.55) | MAPTSMN1; SMN2TP53THRBPDE4B | |
| SCHEMBL8560347 | 0.86 | ERBB2 (0.52) | MAPTSMN1; SMN2TP53THRBNPC1 | |
| SCHEMBL8328461 | 0.86 | MAPT (0.52) | MAPTSMN1; SMN2TP53THRBPDE4B | |
| SCHEMBL8559604 | 0.85 | MAPT (0.62) | MAPTSMN1; SMN2TP53THRBPDE4B | |
| Hydrochloric Acid SCHEMBL8328640 | 0.85 | MAPT (0.51) | MAPTSMN1; SMN2TP53THRBPDE4B | |
| Hydrochloric Acid SCHEMBL8566240 | 0.85 | ERBB2 (0.51) | MAPTSMN1; SMN2TP53THRBNPC1 | |
| SCHEMBL8323681 | 0.85 | MAPT (0.49) | MAPTSMN1; SMN2TP53THRBPDE4B | |
| Hydrochloric Acid SCHEMBL8561142 | 0.84 | MAPT (0.61) | MAPTSMN1; SMN2TP53THRBPDE4B | |
| Hydrochloric Acid SCHEMBL8330804 | 0.84 | MAPT (0.49) | MAPTSMN1; SMN2TP53THRBPDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993013097-A1 | ANTI-RHEUMATIC NAPHTHYRIDINE DERIVATIVES | THE BOOTS COMPANY PLC (GB) | 1993-07-08 | — | — | WO | disclosed |