Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERBB2 | P04626 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | RAD52 | P43351 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | EPHB2 | P29323 | 1/20 | 0.41 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8566240 | 0.99 | ERBB2 (0.51) | ERBB2RAB9AFGFR2POLBMAPT | |
| SCHEMBL8325406 | 0.90 | PDE10A (0.41) | ERBB2RAB9AFGFR2POLBMAPT | |
| Hydrochloric Acid SCHEMBL8468831 | 0.88 | PDE10A (0.42) | ERBB2RAB9AFGFR2POLBMAPT | |
| SCHEMBL8559967 | 0.88 | PDGFRA (0.48) | RAB9AFGFR2POLBMAPTRAD52 | |
| Water SCHEMBL8328226 | 0.87 | PDGFRA (0.47) | RAB9AFGFR2POLBMAPTRAD52 | |
| Hydrochloric Acid SCHEMBL8566059 | 0.87 | HTT (0.50) | RAB9AFGFR2POLBMAPTRAD52 | |
| SCHEMBL9541717 | 0.86 | MAPT (0.50) | MAPTKDM4ETP53SMN1; SMN2THRB | |
| SCHEMBL8567323 | 0.84 | MAPKAPK2 (0.46) | RAB9APOLBMAPTKMT2ANPSR1 | |
| SCHEMBL8327641 | 0.82 | POLB (0.37) | POLBKMT2AL3MBTL1RIPK2EGFR | |
| SCHEMBL8568868 | 0.81 | HRH3 (0.49) | EHMT2KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0618916-B1 | ANTI-RHEUMATIC NAPHTHYRIDINE DERIVATIVES | KNOLL AG (DE) | 1998-09-23 | — | — | EP | disclosed |
| US-5464781-A | TREATING RHEUMATIC DISEASES | THE BOOTS COMPANY PLC (GB) | 1995-11-07 | — | — | US | disclosed |
| EP-0618916-A1 | ANTI-RHEUMATIC NAPHTHYRIDINE DERIVATIVES | Knoll AG (DE) | 1994-10-12 | — | — | EP | disclosed |