SCHEMBL9541767

SCHEMBL9541767

Nc1sc(C=O)nc1C(=CCl)C(=O)O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16458540 0.65 CYP1A2 (0.37)
SCHEMBL11272804 0.61 CSNK2A1 (0.39)
SCHEMBL11272806 0.61 CSNK2A1 (0.39)
SCHEMBL10916107 0.60 ALDH1A1 (0.44)
SCHEMBL10916101 0.60 ALDH1A1 (0.44)
SCHEMBL10428685 0.57 ALDH1A1 (0.36)
SCHEMBL10428686 0.57 ALDH1A1 (0.36)
SCHEMBL10922281 0.56 DAO (0.59)
SCHEMBL11261423 0.56 DAO (0.59)
SCHEMBL25406990 0.56 HCAR2 (0.54)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1993013108-A1 SUBSTITUTED 3-CEPHEM COMPOUNDS AS ANTIBACTERIAL AGENTS NAKANISHI SUSUMU (US) 1993-07-08 WO disclosed
EP-0082498-A2 Beta-lactam compounds and process for the preparation thereof SAGAMI CHEMICAL RESEARCH CENTER (JP) 1983-06-29 EP disclosed
EP-0048954-A2 Beta-lactam compounds, process for the preparation thereof and intermediate products for the preparation thereof SAGAMI CHEMICAL RESEARCH CENTER (JP) 1982-04-07 EP disclosed