Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A1 | P18405 | 11/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 7/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9542235 | 1.00 | SRD5A1 (0.41) | SRD5A1SRD5A2AR | |
| SCHEMBL7142783 | 0.83 | SRD5A2 (0.61) | SRD5A1SRD5A2AR | |
| SCHEMBL7624258 | 0.83 | SRD5A2 (0.61) | SRD5A1SRD5A2AR | |
| SCHEMBL8611670 | 0.74 | SRD5A2 (0.65) | SRD5A2 | |
| SCHEMBL8611675 | 0.74 | SRD5A2 (0.65) | SRD5A2 | |
| SCHEMBL9328395 | 0.73 | SRD5A2 (0.61) | SRD5A1SRD5A2 | |
| SCHEMBL9417979 | 0.71 | AR (0.49) | SRD5A2AR | |
| SCHEMBL9457741 | 0.69 | SRD5A2 (0.39) | SRD5A1SRD5A2 | |
| SCHEMBL8158262 | 0.69 | SRD5A1 (0.66) | SRD5A1SRD5A2 | |
| SCHEMBL8158267 | 0.69 | SRD5A1 (0.66) | SRD5A1SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993014762-A1 | 17β-HYDROXYBENZOYL-4-AZA-5α-ANDROST-1-EN-3-ONES USEFUL TO TREAT BALDNESS | MERCK & CO., INC. (US) | 1993-08-05 | — | — | WO | disclosed |
| EP-0414490-A2 | 17 Beta-acyl-4-aza-5 alpha-androst-1-ene-3-one as 5 alpha-reductase inhibitors | MERCK & CO. INC. (US) | 1991-02-27 | — | — | EP | disclosed |