Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Acetamide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.57 |
| ▸ | BLM | P54132 | 2/20 | 0.57 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.57 |
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
| ▸ | GABRR1 | P24046 | 3/20 | 0.33 |
| ▸ | OR51E2 | Q9H255 | 2/20 | 0.33 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.33 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.33 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.32 |
| ▸ | GABRP | O00591 | 1/20 | 0.32 |
| ▸ | GABRD | O14764 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetamide SCHEMBL66201 | 1.00 | — | — | |
| Acetamide SCHEMBL27889087 | 0.97 | — | — | |
| Acetone SCHEMBL8811076 | 0.89 | — | — | |
| Acetone SCHEMBL10591911 | 0.89 | ALDH1A1 (0.61) | LMNAALDH1A1TSHRALOX15BLM | |
| Acetic Acid SCHEMBL503041 | 0.86 | — | — | |
| Acetic Acid SCHEMBL2140076 | 0.86 | ALDH1A1 (0.57) | LMNAALDH1A1TSHRALOX15BLM | |
| Acetic Acid SCHEMBL11054868 | 0.86 | ALDH1A1 (0.57) | LMNAALDH1A1TSHRALOX15BLM | |
| Acetic Acid SCHEMBL28674854 | 0.86 | ALDH1A1 (0.57) | LMNAALDH1A1TSHRALOX15BLM | |
| Acetone SCHEMBL16733018 | 0.86 | — | — | |
| Acetic Acid SCHEMBL5819601 | 0.86 | ALDH1A1 (0.57) | LMNAALDH1A1TSHRALOX15BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993010753-A1 | UVA-ABSORBING SUNSCREEN METAL COMPLEXES | RICHARDSON-VICKS, INC. (US) | 1993-06-10 | — | — | WO | disclosed |