Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | PRNP | P04156 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14353167 | 0.86 | LMNA (0.45) | LMNATSHRALDH1A1HPGDMAPT | |
| SCHEMBL12056607 | 0.80 | LMNA (0.45) | LMNATSHRALDH1A1HPGDMAPT | |
| SCHEMBL283888 | 0.77 | LMNA (0.45) | LMNATSHRALDH1A1HPGDMAPT | |
| SCHEMBL2911453 | 0.75 | LMNA (0.37) | LMNATSHRALDH1A1HPGDMAPT | |
| SCHEMBL9619467 | 0.75 | — | — | |
| SCHEMBL128912 | 0.74 | — | — | |
| SCHEMBL17123871 | 0.74 | CYP1A2 (0.38) | LMNATSHRALDH1A1HPGDMAPT | |
| SCHEMBL7032255 | 0.74 | TSHR (0.38) | LMNATSHRALDH1A1HPGDMAPT | |
| SCHEMBL7460510 | 0.74 | LMNA (0.36) | LMNATSHRALDH1A1HPGDMAPT | |
| SCHEMBL10174626 | 0.73 | LMNA (0.47) | LMNATSHRALDH1A1HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993013664-A2 | BIHETEROCYCLIC FUNGICIDAL COMPOUNDS | SCHERING AGROCHEMICALS LIMITED (GB) | 1993-07-22 | — | — | WO | disclosed |