SCHEMBL9542497

SCHEMBL9542497

CSc1ncc2c(O)c(C(=O)OC3CCCCC3)sc2n1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.47
HSD17B10 Q99714 3/20 0.47
HPGD P15428 2/20 0.47
ALOX15 P16050 2/20 0.35
TSHR P16473 1/20 0.35
NPC1 O15118 2/20 0.34
RAB9A P51151 2/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
MEN1 O00255 3/20 0.33
KMT2A Q03164 3/20 0.33
MAPT P10636 2/20 0.32
CYP1A2 P05177 1/20 0.32
CYP3A4 P08684 1/20 0.32
GAA P10253 1/20 0.32
PDE4B Q07343 1/20 0.31
KDM4E B2RXH2 1/20 0.31
HTT P42858 1/20 0.31
MMP1 P03956 1/20 0.31
MMP9 P14780 1/20 0.31
MMP12 P39900 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9541076 0.84 ALDH1A1 (0.47) ALDH1A1HSD17B10HPGDALOX15TSHR
SCHEMBL9540994 0.82 ALDH1A1 (0.46) ALDH1A1HSD17B10HPGDNPC1RAB9A
SCHEMBL27403724 0.81 ALDH1A1 (0.44) ALDH1A1HSD17B10HPGDTSHRNPC1
SCHEMBL9542516 0.80 KDM4E (0.40) ALDH1A1HPGDNPC1RAB9ASMN1; SMN2
SCHEMBL9542510 0.80 ALDH1A1 (0.47) ALDH1A1HSD17B10HPGDALOX15NPC1
SCHEMBL9542662 0.78 ALDH1A1 (0.41) ALDH1A1HSD17B10HPGDTSHRNPC1
SCHEMBL9540890 0.76 ALDH1A1 (0.43) ALDH1A1HSD17B10HPGDALOX15TSHR
SCHEMBL9542502 0.74 ALDH1A1 (0.38) ALDH1A1HSD17B10HPGDALOX15TSHR
SCHEMBL9541065 0.74 ALDH1A1 (0.46) ALDH1A1HSD17B10HPGDKMT2AMAPT
SCHEMBL9541191 0.74 KMT2A (0.42) ALDH1A1HSD17B10HPGDNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1993013664-A2 BIHETEROCYCLIC FUNGICIDAL COMPOUNDS SCHERING AGROCHEMICALS LIMITED (GB) 1993-07-22 WO disclosed