Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.47 |
| ▸ | MC4R | P32245 | 2/20 | 0.41 |
| ▸ | MC5R | P33032 | 1/20 | 0.41 |
| ▸ | MC3R | P41968 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MPO | P05164 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | ACE | P12821 | 1/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.40 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9543725 | 0.94 | DPP4 (0.46) | DPP4HDAC8MC4RMC5RMC3R | |
| SCHEMBL9542629 | 0.88 | MAPT (0.47) | DPP4MC4RMC5RMC3RKDM4E | |
| SCHEMBL9543952 | 0.82 | MAPT (0.45) | DPP4MC4RMC5RMC3RKDM4E | |
| SCHEMBL9545084 | 0.81 | MAPT (0.47) | DPP4MC4RMC5RMC3RKDM4E | |
| SCHEMBL27871523 | 0.80 | MAPT (0.58) | MC4RMC5RMC3RKDM4EMEN1 | |
| SCHEMBL9544862 | 0.79 | MAPT (0.47) | DPP4KDM4EMEN1LMNAMPO | |
| SCHEMBL28784184 | 0.78 | TACR1 (0.54) | MC4RMC5RMC3RKDM4EMEN1 | |
| SCHEMBL5022639 | 0.78 | DPP4 (0.63) | DPP4HDAC8KDM4EMEN1LMNA | |
| SCHEMBL9543664 | 0.78 | MAPT (0.45) | DPP4KDM4EMEN1LMNAMPO | |
| SCHEMBL27871519 | 0.76 | TACR1 (0.51) | MC4RMC5RMC3RKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993020099-A2 | CCK AND/OR GASTRIN RECEPTOR LIGANDS | FERRING B.V. (NL) | 1993-10-14 | — | — | WO | disclosed |