Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | CTSL | P07711 | 4/20 | 0.44 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 2/20 | 0.40 |
| ▸ | SNCA | P37840 | 7/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MPO | P05164 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9543952 | 0.91 | MAPT (0.45) | MAPTALDH1A1RAB9ACTSLDPP4 | |
| SCHEMBL9542629 | 0.90 | MAPT (0.47) | MAPTALDH1A1RAB9ACTSLDPP4 | |
| SCHEMBL9544862 | 0.90 | MAPT (0.47) | MAPTALDH1A1RAB9ACTSLDPP4 | |
| SCHEMBL9545084 | 0.90 | MAPT (0.47) | MAPTALDH1A1RAB9ACTSLCTSK | |
| SCHEMBL9544895 | 0.85 | DPP4 (0.40) | MAPTALDH1A1DPP4BCHEKDM4E | |
| SCHEMBL9543725 | 0.80 | DPP4 (0.46) | MAPTDPP4BCHEKDM4EMEN1 | |
| SCHEMBL9542526 | 0.78 | DPP4 (0.47) | MAPTDPP4BCHEKDM4EMEN1 | |
| SCHEMBL27871523 | 0.77 | MAPT (0.58) | MAPTCTSLCTSKKDM4EMEN1 | |
| SCHEMBL9543677 | 0.77 | CTSL (0.63) | MAPTCTSLCTSK | |
| SCHEMBL27871519 | 0.75 | TACR1 (0.51) | MAPTCTSLCTSKKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993020099-A2 | CCK AND/OR GASTRIN RECEPTOR LIGANDS | FERRING B.V. (NL) | 1993-10-14 | — | — | WO | claimed |
| WO-1993020099-A2 | CCK AND/OR GASTRIN RECEPTOR LIGANDS | FERRING B.V. (NL) | 1993-10-14 | — | — | WO | disclosed |