Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 4/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9542522 | 1.00 | CYP19A1 (0.39) | CYP19A1CYP3A4TP53MAPTSMN1; SMN2 | |
| SCHEMBL15469938 | 1.00 | CYP19A1 (0.39) | CYP19A1CYP3A4TP53MAPTSMN1; SMN2 | |
| SCHEMBL12699075 | 1.00 | CYP19A1 (0.39) | CYP19A1CYP3A4TP53MAPTSMN1; SMN2 | |
| SCHEMBL12969935 | 0.83 | CYP3A4 (0.39) | CYP3A4TP53MAPTSMN1; SMN2CYP2C19 | |
| SCHEMBL12804123 | 0.83 | CYP3A4 (0.39) | CYP3A4TP53MAPTSMN1; SMN2CYP2C19 | |
| SCHEMBL6300889 | 0.80 | NPC1L1 (0.55) | TP53MEN1LMNAKMT2A | |
| SCHEMBL16163620 | 0.80 | NPC1L1 (0.55) | TP53MEN1LMNAKMT2A | |
| SCHEMBL9133868 | 0.80 | NPC1L1 (0.55) | TP53MEN1LMNAKMT2A | |
| SCHEMBL14976644 | 0.80 | USP2 (0.50) | TP53MAPTMEN1LMNAKMT2A | |
| SCHEMBL6303110 | 0.80 | NPC1L1 (0.55) | TP53MEN1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993014105-A1 | DIFLUOROMETHYLENANDROSTENONE DERIVATIVES AND PROCESS FOR THEIR PREPARATION | FARMITALIA CARLO ERBA S.R.L. (IT) | 1993-07-22 | — | — | WO | disclosed |