Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 2/20 | 0.50 |
| ▸ | VDR | P11473 | 1/20 | 0.50 |
| ▸ | NPC1L1 | Q9UHC9 | 6/20 | 0.44 |
| ▸ | POLA1 | P09884 | 1/20 | 0.43 |
| ▸ | TOP2A | P11388 | 1/20 | 0.43 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | CDC25A | P30304 | 1/20 | 0.40 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | ST6GAL1 | P15907 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16163667 | 1.00 | USP2 (0.50) | USP2VDRNPC1L1POLA1TOP2A | |
| SCHEMBL6300887 | 0.90 | NPC1L1 (0.55) | USP2VDRNPC1L1POLA1MEN1 | |
| SCHEMBL6303110 | 0.90 | NPC1L1 (0.55) | USP2VDRNPC1L1POLA1MEN1 | |
| SCHEMBL6300889 | 0.90 | NPC1L1 (0.55) | USP2VDRNPC1L1POLA1MEN1 | |
| SCHEMBL9133868 | 0.90 | NPC1L1 (0.55) | USP2VDRNPC1L1POLA1MEN1 | |
| SCHEMBL16163620 | 0.90 | NPC1L1 (0.55) | USP2VDRNPC1L1POLA1MEN1 | |
| SCHEMBL26333487 | 0.88 | VDR (0.53) | USP2VDRNPC1L1POLA1TOP2A | |
| SCHEMBL1312863 | 0.87 | NPC1L1 (0.55) | USP2VDRNPC1L1POLA1TOP2A | |
| SCHEMBL9542522 | 0.80 | CYP19A1 (0.39) | MEN1LMNATP53KMT2AMAPT | |
| SCHEMBL9542528 | 0.80 | CYP19A1 (0.39) | MEN1LMNATP53KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2782923-A1 | PROCESS FOR THE PREPARATION OF STEROL DERIVATIVES | INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) | 2014-10-01 | — | — | EP | disclosed |
| WO-2013076257-A1 | PROCESS FOR THE PREPARATION OF STEROL DERIVATIVES | INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) | 2013-05-30 | — | — | WO | disclosed |