Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 1.00 |
| ▸ | NPC1 | O15118 | 1/20 | 1.00 |
| ▸ | HTT | P42858 | 1/20 | 1.00 |
| ▸ | RAB9A | P51151 | 1/20 | 1.00 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 1.00 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | MMP14 | P50281 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7167399 | 0.82 | MAPT (0.70) | MAPTNPC1HTTRAB9ANPSR1 | |
| SCHEMBL2980631 | 0.74 | MAPT (0.58) | MAPTNPC1HTTRAB9ANPSR1 | |
| SCHEMBL216700 | 0.74 | MAPT (0.58) | MAPTNPC1HTTRAB9ANPSR1 | |
| SCHEMBL30978772 | 0.73 | MAPT (0.57) | MAPTNPC1HTTRAB9ANPSR1 | |
| SCHEMBL3073488 | 0.72 | MAPT (0.56) | MAPTNPC1HTTRAB9ANPSR1 | |
| SCHEMBL1462546 | 0.72 | MAPT (0.56) | MAPTNPC1HTTRAB9ANPSR1 | |
| SCHEMBL11573741 | 0.71 | RAB9A (0.53) | MAPTNPC1HTTRAB9ANPSR1 | |
| SCHEMBL1157660 | 0.70 | MAPT (0.55) | MAPTNPC1HTTRAB9ANPSR1 | |
| Hydrochloric Acid SCHEMBL11851685 | 0.70 | MAPT (0.54) | MAPTNPC1HTTRAB9ANPSR1 | |
| SCHEMBL4052304 | 0.70 | MAPT (0.54) | MAPTNPC1HTTRAB9ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993013664-A2 | BIHETEROCYCLIC FUNGICIDAL COMPOUNDS | SCHERING AGROCHEMICALS LIMITED (GB) | 1993-07-22 | — | — | WO | disclosed |
| US-4399075-A | Process for producing chlorinated phenoxytoluene derivatives | ASAHI CHEMICAL COMPANY, LIMITED (JP) | 1983-08-16 | — | — | US | disclosed |