Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.59 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.47 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 2/20 | 0.45 |
| ▸ | GSK3B | P49841 | 2/20 | 0.45 |
| ▸ | GSK3A | P49840 | 1/20 | 0.45 |
| ▸ | PRKAG1 | P54619 | 3/20 | 0.44 |
| ▸ | PRKAA1 | Q13131 | 3/20 | 0.44 |
| ▸ | PRKAB1 | Q9Y478 | 3/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | MME | P08473 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | MYC | P01106 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1713 | 0.83 | ESR2 (0.67) | ESR2FFAR1AKR1B1PTPN5PPARG | |
| SCHEMBL31410710 | 0.82 | ESR2 (0.76) | ESR2FFAR1AKR1B1PTPN5PPARG | |
| SCHEMBL29170999 | 0.81 | ESR2 (0.59) | ESR2FFAR1AKR1B1PTPN5PPARG | |
| SCHEMBL357 | 0.81 | ESR2 (0.59) | ESR2FFAR1AKR1B1PTPN5PPARG | |
| SCHEMBL360601 | 0.81 | ESR2 (0.59) | ESR2FFAR1AKR1B1PTPN5PPARG | |
| SCHEMBL31772593 | 0.81 | ESR2 (0.59) | ESR2FFAR1AKR1B1PTPN5PPARG | |
| SCHEMBL3169219 | 0.81 | ESR2 (0.59) | ESR2FFAR1AKR1B1PTPN5PPARG | |
| SCHEMBL7867991 | 0.81 | ESR2 (0.59) | ESR2FFAR1AKR1B1PTPN5PPARG | |
| SCHEMBL31124937 | 0.81 | ESR2 (0.59) | ESR2FFAR1AKR1B1PTPN5PPARG | |
| SCHEMBL26016200 | 0.81 | ESR2 (0.59) | ESR2FFAR1AKR1B1PTPN5PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993014086-A1 | SUBSTITUTED 1-ISOQUINOLONE DERIVATIVES AS ANGIOTENSIN II ANTAGONISTS | SYNTEX (U.S.A.) INC. (US) | 1993-07-22 | — | — | WO | disclosed |