Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 5/20 | 0.43 |
| ▸ | PREP | P48147 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.40 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9543213 | 0.96 | ACE (0.43) | ACEPREPPOLBABCB11TDP1 | |
| SCHEMBL9542649 | 0.91 | PREP (0.39) | ACEPREPCXCR3 | |
| SCHEMBL9543406 | 0.87 | PTPN1 (0.38) | ACEPREPCXCR3 | |
| SCHEMBL9544776 | 0.87 | ACE (0.40) | ACE | |
| SCHEMBL9543455 | 0.86 | POLB (0.39) | ACEPOLBTDP1 | |
| SCHEMBL9542729 | 0.84 | ACE (0.36) | ACE | |
| SCHEMBL9543652 | 0.84 | ACE (0.38) | ACE | |
| SCHEMBL9544913 | 0.82 | ACE (0.41) | ACE | |
| SCHEMBL9544819 | 0.82 | DRD4 (0.38) | TDP1 | |
| SCHEMBL9544446 | 0.82 | HDAC8 (0.36) | PREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993020099-A2 | CCK AND/OR GASTRIN RECEPTOR LIGANDS | FERRING B.V. (NL) | 1993-10-14 | — | — | WO | claimed |
| WO-1993020099-A2 | CCK AND/OR GASTRIN RECEPTOR LIGANDS | FERRING B.V. (NL) | 1993-10-14 | — | — | WO | disclosed |