Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | HTR1A | P08908 | 2/20 | 0.38 |
| ▸ | HTR7 | P34969 | 2/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ACE | P12821 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9545071 | 0.92 | DRD2 (0.37) | HTR1AHTR7DRD2DRD4MAPT | |
| SCHEMBL9543213 | 0.89 | ACE (0.43) | POLBTDP1L3MBTL1ACE | |
| SCHEMBL9543363 | 0.88 | DRD2 (0.41) | DRD2DRD4MAPT | |
| SCHEMBL9542641 | 0.86 | ACE (0.43) | POLBTDP1ACE | |
| SCHEMBL9542696 | 0.85 | LMNA (0.42) | DRD2DRD4MAPT | |
| SCHEMBL9543221 | 0.82 | DRD2 (0.35) | POLBHTR1AHTR7DRD2DRD4 | |
| SCHEMBL9543406 | 0.80 | PTPN1 (0.38) | ACE | |
| SCHEMBL9543510 | 0.80 | ALDH1A1 (0.43) | DRD2DRD4 | |
| SCHEMBL9542741 | 0.79 | CFTR (0.37) | MAPT | |
| SCHEMBL9542729 | 0.78 | ACE (0.36) | ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993020099-A2 | CCK AND/OR GASTRIN RECEPTOR LIGANDS | FERRING B.V. (NL) | 1993-10-14 | — | — | WO | disclosed |