Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 1/20 | 0.51 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.43 |
| ▸ | F11 | P03951 | 1/20 | 0.42 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.42 |
| ▸ | CCR1 | P32246 | 2/20 | 0.42 |
| ▸ | PPIA | P62937 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KCNJ6 | P48051 | 2/20 | 0.41 |
| ▸ | KCNJ5 | P48544 | 2/20 | 0.41 |
| ▸ | KCNJ3 | P48549 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9543766 | 1.00 | CCKBR (0.51) | CCKBRGRIN2BF11KLKB1CCR1 | |
| SCHEMBL9542459 | 0.89 | CCKBR (0.49) | CCKBRGRIN2BF11KLKB1CCR1 | |
| SCHEMBL9542455 | 0.89 | CCKBR (0.49) | CCKBRGRIN2BF11KLKB1CCR1 | |
| SCHEMBL9542723 | 0.84 | CCKBR (0.51) | CCKBRPPIAMAPK1 | |
| SCHEMBL9542726 | 0.84 | CCKBR (0.51) | CCKBRPPIAMAPK1 | |
| SCHEMBL9543592 | 0.84 | CCKBR (0.53) | CCKBRCCR1PPIALMNAKCNJ6 | |
| SCHEMBL9543587 | 0.84 | CCKBR (0.53) | CCKBRCCR1PPIALMNAKCNJ6 | |
| SCHEMBL9543775 | 0.83 | GRIN2B (0.45) | GRIN2BF11KLKB1CCR1LMNA | |
| SCHEMBL9544800 | 0.79 | ELANE (0.49) | MEN1KMT2A | |
| SCHEMBL9544805 | 0.79 | ELANE (0.49) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993020099-A2 | CCK AND/OR GASTRIN RECEPTOR LIGANDS | FERRING B.V. (NL) | 1993-10-14 | — | — | WO | claimed |
| WO-1993020099-A2 | CCK AND/OR GASTRIN RECEPTOR LIGANDS | FERRING B.V. (NL) | 1993-10-14 | — | — | WO | disclosed |