Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.37 |
| ▸ | HTT | P42858 | 4/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7356554 | 0.86 | MAPT (0.55) | MAPTALDH1A1KCNMA1MEN1KMT2A | |
| SCHEMBL7350188 | 0.82 | MAPT (0.58) | MAPTALDH1A1KCNMA1MEN1KMT2A | |
| SCHEMBL7955855 | 0.77 | MAPK1 (0.55) | MAPTALDH1A1KCNMA1MEN1KMT2A | |
| SCHEMBL7358391 | 0.71 | PLK1 (0.40) | MAPTALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7350226 | 0.69 | MAPT (0.65) | MAPTALDH1A1KCNMA1MEN1KMT2A | |
| SCHEMBL7358247 | 0.68 | MAPT (0.61) | MAPTALDH1A1KCNMA1MEN1KMT2A | |
| SCHEMBL7355650 | 0.67 | MAPT (0.62) | MAPTALDH1A1KCNMA1MEN1KMT2A | |
| SCHEMBL28745633 | 0.66 | MAPT (0.70) | MAPTALDH1A1KCNMA1MEN1KMT2A | |
| SCHEMBL7359035 | 0.65 | KDM4E (0.52) | MAPTALDH1A1MEN1KMT2AGAA | |
| SCHEMBL116538 | 0.65 | MAPK1 (0.62) | MAPTALDH1A1KCNMA1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993008173-A1 | QUINOXALINE DERIVATES WITH AFFINITY FOR QUISQUALATE-RECEPTORS | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-04-29 | — | — | WO | disclosed |