Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | ESR1 | P03372 | 4/20 | 0.51 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.51 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.51 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.51 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.51 |
| ▸ | CNR2 | P34972 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1127490 | 0.85 | CA12 (0.56) | MAPK1CYP3A4ALDH1A1LMNAKDM4E | |
| Ammonia Solution, Strong SCHEMBL15940166 | 0.82 | TSHR (0.59) | TSHRMAPK1TP53CYP3A4ALDH1A1 | |
| SCHEMBL15910310 | 0.80 | TSHR (0.58) | TSHRMAPK1TP53CYP3A4ALDH1A1 | |
| SCHEMBL11152364 | 0.80 | TSHR (0.56) | TSHRMAPK1TP53CYP3A4ALDH1A1 | |
| SCHEMBL11103392 | 0.78 | TSHR (0.63) | TSHRMAPK1TP53CYP3A4ALDH1A1 | |
| SCHEMBL11878219 | 0.78 | TSHR (0.55) | TSHRMAPK1TP53CYP3A4ALDH1A1 | |
| SCHEMBL11162266 | 0.77 | TSHR (0.64) | TSHRMAPK1TP53CYP3A4ALDH1A1 | |
| SCHEMBL6501360 | 0.77 | MEN1 (0.54) | TSHRMAPK1CYP3A4ALDH1A1LMNA | |
| SCHEMBL27870896 | 0.77 | TSHR (0.68) | TSHRMAPK1TP53CYP3A4ALDH1A1 | |
| SCHEMBL17950774 | 0.77 | TSHR (0.54) | TSHRMAPK1TP53CYP3A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5179476-A | — | — | None | — | — | JP | disclosed |
| JP-H05179476-A | PRODUCTION OF 1,4-DIHYDROXY-2-NAPHTHOIC ACID ARYL ESTER | OSAKA CITY | 1993-07-20 | — | — | JP | disclosed |