Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | CA7 | P43166 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.54 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | GAA | P10253 | 4/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | RECQL | P46063 | 2/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10905131 | 0.88 | CYP3A4 (0.55) | CA12CA1CA2CA7CA9 | |
| SCHEMBL9542801 | 0.85 | TSHR (0.52) | ALDH1A1KDM4ECYP3A4LMNAMAPK1 | |
| SCHEMBL6501360 | 0.83 | MEN1 (0.54) | CA12CA1CA2CA7CA9 | |
| SCHEMBL5835576 | 0.82 | CA12 (0.55) | CA12CA1CA2CA7CA9 | |
| SCHEMBL1590707 | 0.82 | ALDH1A1 (0.65) | CA12CA1CA2CA7CA9 | |
| SCHEMBL8347077 | 0.81 | SMN1; SMN2 (0.55) | CA12CA1CA2CA7CA9 | |
| SCHEMBL6265168 | 0.80 | ALOX5 (0.63) | CA12CA1CA2CA7CA9 | |
| SCHEMBL31643781 | 0.80 | ALOX5 (0.63) | CA12CA1CA2CA7CA9 | |
| SCHEMBL28261477 | 0.79 | ALDH1A1 (0.61) | CA12CA1CA2CA7CA9 | |
| SCHEMBL11315535 | 0.78 | NR1H2 (0.71) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11708480-B2 | Rubber composition, tire, additive and hydrazide compound | OTSUKA CHEMICAL CO., LTD. (JP) | 2023-07-25 | — | — | US | disclosed |
| CN-109563316-B | Rubber composition, tire, additive and hydrazide compound | 株式会社普利司通 | 2021-08-17 | — | — | CN | disclosed |
| EP-3495415-B1 | RUBBER COMPOSITION, TIRE, ADDITIVE, AND HYDRAZIDE COMPOUND | BRIDGESTONE CORP (JP) | 2021-01-20 | — | — | EP | disclosed |
| WO-2019156094-A1 | RUBBER COMPOSITION AND TIRE | 株式会社ブリヂストン | 2019-08-15 | — | — | WO | disclosed |
| WO-2019156093-A1 | RUBBER COMPOSITION AND TIRE | 株式会社ブリヂストン | 2019-08-15 | — | — | WO | disclosed |
| US-20190177513-A1 | RUBBER COMPOSITION, TIRE, ADDITIVE AND HYDRAZIDE | BRIDGESTONE CORPORATION (JP) | 2019-06-13 | — | — | US | disclosed |
| EP-3495415-A1 | RUBBER COMPOSITION, TIRE, ADDITIVE, AND HYDRAZIDE COMPOUND | Bridgestone Corporation (JP) | 2019-06-12 | — | — | EP | disclosed |
| EP-2283002-A2 | NOVEL INHIBITORS OF HEPATITIS C VIRUS REPLICATION | Intermune, Inc. (US) | 2011-02-16 | — | — | EP | disclosed |
| WO-2009134616-A2 | NOVEL INHIBITORS OF HEPATITIS C VIRUS REPLICATION | INTERMUNE, INC. (US) | 2009-11-05 | — | — | WO | disclosed |
| WO-2009134616-A2 | NOVEL INHIBITORS OF HEPATITIS C VIRUS REPLICATION | INTERMUNE, INC. (US) | 2009-11-05 | — | — | WO | disclosed |
| US-20090257979-A1 | Novel Inhibitors of Hepatitis C Virus Replication | INTERMUNE, INC. (US) | 2009-10-15 | — | — | US | disclosed |
| US-20090257979-A1 | Novel Inhibitors of Hepatitis C Virus Replication | INTERMUNE, INC. (US) | 2009-10-15 | — | — | US | disclosed |
| US-20090257979-A1 | Novel Inhibitors of Hepatitis C Virus Replication | INTERMUNE, INC. (US) | 2009-10-15 | — | — | US | disclosed |
| CN-1142174-C | Optical information gene material and its application in gene chip technology | 南开大学 | 2004-03-17 | — | — | CN | disclosed |
| CN-1332174-A | Optical information gene material and its application in gene chip technology | UNIV NANKAI (CN) | 2002-01-23 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090257979-A1 | Novel Inhibitors of Hepatitis C Virus Replication | EIF2AK2, HAVCR2, HDGF | CA12 4494/4885CA1 4719/4885CA2 4358/4885 |
| US-20190177513-A1 | RUBBER COMPOSITION, TIRE, ADDITIVE AND HYDRAZIDE | HRH2, HRH1, HEATR1 | CA12 4621/4885CA1 3503/4885CA2 3917/4885 |
| US-11708480-B2 | Rubber composition, tire, additive and hydrazide compound | HRH2, HRH1, HEATR1 | CA12 4590/4885CA1 3693/4885CA2 3980/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.