Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CCNC | P24863 | 4/20 | 0.43 |
| ▸ | CDK8 | P49336 | 4/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.43 |
| ▸ | PRKCI | P41743 | 1/20 | 0.38 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 2/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18962969 | 0.86 | MAPT (0.52) | MAPTCYP3A4KDM4EMEN1TP53 | |
| Hydrochloric Acid SCHEMBL27386294 | 0.85 | HTR2C (0.53) | MAPTCYP3A4KDM4EMEN1TP53 | |
| SCHEMBL9545377 | 0.84 | MEN1 (0.41) | MAPTCYP3A4KDM4EMEN1TP53 | |
| SCHEMBL9544511 | 0.82 | MAPT (0.42) | MAPTCYP3A4KDM4EMEN1TP53 | |
| SCHEMBL9543681 | 0.82 | MAPT (0.46) | MAPTCYP3A4KDM4EMEN1TP53 | |
| SCHEMBL9376868 | 0.82 | HTR2B (0.40) | MAPTCYP3A4KDM4EMEN1TP53 | |
| SCHEMBL9542979 | 0.79 | GRK5 (0.47) | MAPTCYP3A4KDM4EMEN1TP53 | |
| SCHEMBL9545349 | 0.79 | MAPT (0.44) | MAPTCYP3A4KDM4EMEN1TP53 | |
| SCHEMBL9545320 | 0.79 | PIK3CD (0.39) | MAPTCYP3A4KDM4EMEN1TP53 | |
| Hydrochloric Acid SCHEMBL27536002 | 0.78 | HTR2C (0.45) | MAPTCYP3A4KDM4EMEN1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993018028-A1 | INDOLE DERIVATIVES AS 5HT1C ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1993-09-16 | — | — | WO | claimed |