Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRK5 | P34947 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 2/20 | 0.42 |
| ▸ | HTR2C | P28335 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | PLK1 | P53350 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9544563 | 0.86 | HTR2C (0.41) | GRK5HTR2BHTR2CMAPTMEN1 | |
| SCHEMBL9544220 | 0.85 | HTR2B (0.47) | GRK5HTR2BHTR2CMAPTMEN1 | |
| SCHEMBL7098140 | 0.85 | HTR2B (0.42) | GRK5HTR2BHTR2CMAPTMEN1 | |
| SCHEMBL9545059 | 0.84 | GRM4 (0.39) | GRK5HTR2BHTR2CMAPTMEN1 | |
| Hydrochloric Acid SCHEMBL5964207 | 0.84 | HTR2C (0.42) | GRK5HTR2BHTR2CMAPTMEN1 | |
| SCHEMBL9544345 | 0.84 | HTR2B (0.40) | GRK5HTR2BHTR2CMAPTMEN1 | |
| SCHEMBL27469254 | 0.83 | HTR2B (0.40) | HTR2BHTR2CMAPTMEN1KMT2A | |
| SCHEMBL18962969 | 0.83 | MAPT (0.52) | HTR2BHTR2CMAPTMEN1KMT2A | |
| SCHEMBL27407225 | 0.83 | HTR2B (0.39) | GRK5HTR2BHTR2CMAPTMEN1 | |
| Hydrochloric Acid SCHEMBL27386294 | 0.82 | HTR2C (0.53) | HTR2BHTR2CMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993018028-A1 | INDOLE DERIVATIVES AS 5HT1C ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1993-09-16 | — | — | WO | claimed |