Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 1/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.45 |
| ▸ | PPIA | P62937 | 1/20 | 0.41 |
| ▸ | CCR3 | P51677 | 9/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9543237 | 1.00 | CCKBR (0.50) | CCKBROPRM1PPIACCR3OPRD1 | |
| SCHEMBL9542932 | 0.89 | CCKBR (0.60) | CCKBROPRM1OPRD1OPRK1 | |
| SCHEMBL9542936 | 0.89 | CCKBR (0.60) | CCKBROPRM1OPRD1OPRK1 | |
| SCHEMBL9542687 | 0.88 | CCKBR (0.54) | CCKBROPRM1OPRD1OPRK1LMNA | |
| SCHEMBL9543501 | 0.88 | CCKBR (0.50) | CCKBROPRM1PPIAOPRD1OPRK1 | |
| SCHEMBL9542615 | 0.88 | CCKBR (0.50) | CCKBROPRM1OPRD1OPRK1 | |
| SCHEMBL9542689 | 0.88 | CCKBR (0.54) | CCKBROPRM1OPRD1OPRK1LMNA | |
| SCHEMBL9542618 | 0.88 | CCKBR (0.50) | CCKBROPRM1OPRD1OPRK1 | |
| SCHEMBL9543506 | 0.88 | CCKBR (0.50) | CCKBROPRM1PPIAOPRD1OPRK1 | |
| SCHEMBL9544146 | 0.88 | CCKBR (0.49) | CCKBROPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993020099-A2 | CCK AND/OR GASTRIN RECEPTOR LIGANDS | FERRING B.V. (NL) | 1993-10-14 | — | — | WO | claimed |
| WO-1993020099-A2 | CCK AND/OR GASTRIN RECEPTOR LIGANDS | FERRING B.V. (NL) | 1993-10-14 | — | — | WO | disclosed |