Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2RL1 | P55085 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1048210 | 0.90 | F2RL1 (0.38) | F2RL1 | |
| SCHEMBL954747 | 0.87 | F2RL1 (0.37) | F2RL1 | |
| SCHEMBL952844 | 0.87 | F2RL1 (0.35) | F2RL1 | |
| SCHEMBL13256833 | 0.82 | F2RL1 (0.32) | F2RL1 | |
| SCHEMBL6842948 | 0.81 | METTL3 (0.35) | F2RL1 | |
| SCHEMBL6842929 | 0.80 | ATR (0.35) | F2RL1 | |
| SCHEMBL952687 | 0.80 | AKT1 (0.35) | F2RL1 | |
| SCHEMBL13256842 | 0.80 | F2RL1 (0.31) | F2RL1 | |
| SCHEMBL12947617 | 0.80 | F2RL1 (0.31) | F2RL1 | |
| SCHEMBL952549 | 0.79 | F2RL1 (0.34) | F2RL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9139589-B2 | Heteroaryls and uses thereof | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2015-09-22 | — | — | US | disclosed |
| US-20110003806-A1 | Heteroaryls and uses thereof | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2011-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110003806-A1 | Heteroaryls and uses thereof | RICTOR, MTOR, AKT1S1 | F2RL1 1942/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.