Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodomethane SCHEMBL5276176 | 0.96 | HRH3 (0.43) | HRH3KDM4EHTTMEN1POLB | |
| SCHEMBL17526151 | 0.88 | HRH3 (0.42) | HRH3KDM4EHTTALDH1A1SMN1; SMN2 | |
| SCHEMBL9705237 | 0.84 | TSHR (0.44) | HRH3KDM4EHTTMEN1POLB | |
| SCHEMBL31249859 | 0.83 | KDM4E (0.41) | HRH3KDM4EHTTALDH1A1SMN1; SMN2 | |
| SCHEMBL31249866 | 0.81 | HRH3 (0.40) | HRH3KDM4EHTTALDH1A1SMN1; SMN2 | |
| SCHEMBL31249899 | 0.80 | HRH3 (0.47) | HRH3KDM4EHTTALDH1A1SMN1; SMN2 | |
| SCHEMBL17526209 | 0.80 | SIGMAR1 (0.42) | HRH3KDM4EHTTALDH1A1SMN1; SMN2 | |
| SCHEMBL17526208 | 0.80 | HRH3 (0.49) | HRH3ALDH1A1 | |
| SCHEMBL12156673 | 0.79 | HRH3 (0.48) | HRH3 | |
| SCHEMBL17526289 | 0.79 | KDM4E (0.38) | HRH3KDM4EHTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993010883-A1 | LEAN ACID GAS ENRICHMENT WITH SELECTIVE HINDERED AMINES | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1993-06-10 | — | — | WO | disclosed |
| US-4405582-A | Process for selective removal of H2 S from mixtures containing H22 using diaminoether solutions | EXXON RESEARCH AND ENGINEERING CO. (US) | 1983-09-20 | — | — | US | disclosed |
| EP-0087856-A1 | A process for the removal of H2S from gaseous mixtures using diaminoethers | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1983-09-07 | — | — | EP | disclosed |