Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | CCKBR | P32239 | 2/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.38 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9543497 | 1.00 | MAPK1 (0.41) | MAPK1OPRM1OPRD1OPRK1HDAC8 | |
| SCHEMBL9544305 | 0.89 | CCR1 (0.46) | MAPK1OPRM1OPRD1OPRK1NPC1 | |
| SCHEMBL9544299 | 0.89 | CCR1 (0.46) | MAPK1OPRM1OPRD1OPRK1NPC1 | |
| SCHEMBL9542842 | 0.88 | MAPK1 (0.40) | MAPK1OPRM1OPRD1OPRK1NPC1 | |
| SCHEMBL9543501 | 0.88 | CCKBR (0.50) | MAPK1OPRM1OPRD1OPRK1NPC1 | |
| SCHEMBL9543506 | 0.88 | CCKBR (0.50) | MAPK1OPRM1OPRD1OPRK1NPC1 | |
| SCHEMBL9542837 | 0.88 | MAPK1 (0.40) | MAPK1OPRM1OPRD1OPRK1NPC1 | |
| SCHEMBL9542607 | 0.88 | MAPK1 (0.44) | MAPK1OPRM1OPRD1OPRK1NPC1 | |
| SCHEMBL9542781 | 0.87 | CCKBR (0.47) | MAPK1OPRM1OPRD1OPRK1NPC1 | |
| SCHEMBL9542784 | 0.87 | CCKBR (0.47) | MAPK1OPRM1OPRD1OPRK1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993020099-A2 | CCK AND/OR GASTRIN RECEPTOR LIGANDS | FERRING B.V. (NL) | 1993-10-14 | — | — | WO | claimed |
| WO-1993020099-A2 | CCK AND/OR GASTRIN RECEPTOR LIGANDS | FERRING B.V. (NL) | 1993-10-14 | — | — | WO | disclosed |