Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLG | P54098 | 3/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | P2RY2 | P41231 | 8/20 | 0.51 |
| ▸ | P2RY4 | P51582 | 5/20 | 0.51 |
| ▸ | P2RY6 | Q15077 | 3/20 | 0.51 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ALB | P02768 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.41 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.41 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6141732 | 0.92 | POLG (0.59) | POLGPOLBP2RY2P2RY4P2RY6 | |
| SCHEMBL17027928 | 0.90 | POLB (0.56) | POLGPOLBP2RY2P2RY4P2RY6 | |
| SCHEMBL6038227 | 0.90 | POLG (0.57) | POLGPOLBP2RY2P2RY4P2RY6 | |
| SCHEMBL597306 | 0.88 | POLG (0.56) | POLGPOLBP2RY2P2RY4P2RY6 | |
| SCHEMBL10902119 | 0.88 | POLG (0.56) | POLGPOLBP2RY2P2RY4P2RY6 | |
| SCHEMBL25631339 | 0.88 | POLG (0.67) | POLGPOLBP2RY2P2RY4P2RY6 | |
| SCHEMBL24370820 | 0.87 | POLG (0.66) | POLGPOLBP2RY2P2RY4P2RY6 | |
| SCHEMBL27102637 | 0.87 | POLG (0.66) | POLGPOLBP2RY2P2RY4P2RY6 | |
| SCHEMBL3706290 | 0.87 | POLG (0.54) | POLGPOLBP2RY2P2RY4P2RY6 | |
| SCHEMBL5708921 | 0.87 | POLG (0.54) | POLGPOLBP2RY2P2RY4P2RY6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170218416-A1 | COMPOSITIONS AND METHODS FOR SINGLE-MOLECULE CONSTRUCTION OF DNA | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-08-03 | — | — | US | disclosed |
| EP-3143140-A1 | COMPOSITIONS AND METHODS FOR SINGLE-MOLECULE CONSTRUCTION OF DNA | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-03-22 | — | — | EP | disclosed |
| WO-2015176070-A1 | COMPOSITIONS AND METHODS FOR SINGLE-MOLECULE CONSTRUCTION OF DNA | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2015-11-19 | — | — | WO | disclosed |
| WO-1993021311-A1 | IMMORTALISATION OF HUMAN CELLS BY GENE SILENCING | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 1993-10-28 | — | — | WO | disclosed |